Includes support for the Wiimote, so you don't have to use the mouse for it (you're on your own for a sensor bar though), and allows you to output to even 3D 1080p. Aside from that, it's a very great emulator, and is updated often. Notable for being the only emulator out there to play Wii games, which is a godsend for pirates PC gamers. It supports Naomi, Hikaru, and Atomiswave arcade games, but it's also the only that support Windows CE, albeit not too well (Makaron is dead, so it doesn't count), hence why it's on the list. This one may have higher accuracy than NullDC/reicast and redream, but at a performance cost, and it's UI is a bit too cryptic for some, so it isn't recommended for casuals, but there are guides (albeit outdated) for it (ex: ). Needs a high-end PC (NVidia cards are recommended) to run things smoothly.
Oh, and while you're at it, grab some graphic packs as well. Remember to download Cemuhook and get some shader caches here to reduce slowdown.
Wanna play The Legend of Zelda: Breath of the Wild at 1080p resolution and with 60 frames-per-second? This emulator right here should do the trick. Note: byuu only provides a Windows binary, but if you're on macOS or Linux, you can compile from the source or use the Libretro core. bsnes is a subset of multi-system emulator higan, although the standalone version has better performance and a different interface. If your machine can't handle it, use Snes9x instead. The most accurate SNES emulator out there, so it's very demanding.